Pharmaceutical Grade 1,000+ Studies Third-Party Tested

Creatine Monohydrate

Pharmaceutical-Grade Performance, Brain & Longevity Support

★★★★★
(Practitioner reviews)
$49.99

Not all creatine is equal. AvinoCort Creatine Monohydrate is sourced to pharmaceutical standards — the same purity criteria used in clinical research. With over 1,000 published studies, creatine monohydrate is the most thoroughly validated supplement in existence, supporting energy metabolism, muscle health, cognitive function, and healthy aging in patients of all activity levels.*

Beyond bodybuilding. Research supports creatine for brain health, Alzheimer's prevention, metabolic function, mood support, and healthy aging — not just athletic performance.*

Pharmaceutical Grade
Third-Party Tested
GMP Certified

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What Is AvinoCort Creatine?

AvinoCort Creatine Monohydrate is pharmaceutical-grade creatine — sourced and tested to the same purity standards used in clinical research. Creatine is the most studied ergogenic supplement in history, with research validating benefits for physical performance, cognitive function, metabolic health, and healthy aging across diverse patient populations.*

Key Benefits

  • Muscle Energy (ATP) — Replenishes phosphocreatine for sustained output*
  • Physical Performance — Strength, power, and endurance*
  • Brain Health — Cognitive energy, memory, neuroprotection*
  • Metabolic Support — Insulin sensitivity & glucose metabolism*
  • Mood & Wellbeing — Emerging research on depression support*
  • Healthy Aging — Muscle preservation in older adults*
  • Bone Health — Support for bone mineral density*
  • Alzheimer's Risk Reduction — FGF-2 pathway research*

The Phosphocreatine System

Creatine is stored in muscle and brain tissue as phosphocreatine. During high-demand activity — physical or cognitive — phosphocreatine rapidly donates a phosphate group to ADP, regenerating ATP (adenosine triphosphate). This extends the duration and intensity of cellular energy output before fatigue sets in. Daily supplementation keeps phosphocreatine stores fully saturated.*

Creatine Beyond the Gym

Brain: The brain has high ATP demands. Creatine supplementation increases brain phosphocreatine levels, supporting cognitive performance, memory, and neuroprotection — especially relevant in aging populations.*

Metabolic: Research links creatine to improved insulin sensitivity and glucose uptake, making it relevant for metabolic health protocols.*

Mood: Emerging evidence suggests creatine may support serotonin synthesis and reduce depressive symptoms, particularly in females and those with treatment-resistant depression.*

FGF-2 connection: Creatine has been shown to upregulate fibroblast growth factor-2 (FGF-2) in the brain — the same growth factor found in AvinoCort's Humanofort® peptides — providing a mechanistic basis for the synergistic effects in the combo formula.*

Supplement Facts

Supplement Facts
Creatine Monohydrate (Pharma-Grade) 5,000 mg

Dosing

Take 5g daily (approximately 1 teaspoon) with 8–12 oz of water, or as directed by your healthcare practitioner. Mix into water, juice, or a protein shake. Can be taken at any time of day — consistency matters more than timing.*

Quality & Safety

All AvinoCort products are manufactured in GMP-certified facilities and undergo rigorous third-party testing for purity, potency, and safety. Our creatine monohydrate meets pharmaceutical-grade standards used in clinical research.*

Practitioner Notes

Creatine monohydrate is one of the most well-researched supplements available. Consider recommending it for patients seeking cognitive support, metabolic health optimization, or healthy aging protocols — not just athletic performance.*